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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

876 medications

Tick up to 4 to compare.

Walgreen Itch Relief Gel

Diphenhydramine Hydrochloride

Strength
20 mg/mL
Form
Gel
Class
Histamine-1 Receptor Antagonist
OTC

Walgreens

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

Walgreens Stop Itch Gel

Diphenhydramine HCl

Strength
2 g/100mL
Form
Gel
Class
Histamine-1 Receptor Antagonist
OTC

Walgreens Co

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

welby allergy relief

Diphenhydramine Hydrochloride

Strength
25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

Aldi Inc

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

Xpect Extra Strength Itch Relief

Diphenhydramine Hydrochloride

Strength
2 mg/100mL
Form
Spray
Class
Histamine-1 Receptor Antagonist
OTC

Cintas Corporation

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

ZzzQuil

Diphenhydramine Hydrochloride

Strength
50 mg/21
Form
Capsule, Liquid Filled
Class
Histamine-1 Receptor Antagonist
OTC

Lil' Drug Store Products, Inc.

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

ZzzQuil Nighttime Sleep-Aid

DIPHENHYDRAMINE HYDROCHLORIDE

Strength
50 mg/30mL
Form
Liquid
Class
Histamine-1 Receptor Antagonist
OTC

The Procter & Gamble Manufacturing Company

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

ZzzQuil Nighttime Sleep-Aid

Diphenhydramine Hydrochloride

Strength
25 mg/1
Form
Capsule, Gelatin Coated
Class
Histamine-1 Receptor Antagonist
OTC

The Procter & Gamble Manufacturing Company

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

ZzzQuil Nighttime Sleep-Aid

DIPHENHYDRAMINE HYDROCHLORIDE

Strength
50 mg/30mL
Form
Liquid
Class
Histamine-1 Receptor Antagonist
OTC

The Procter & Gamble Manufacturing Company

$4.20 We supply Generic Motrin 400 mg (different strength or form) View product

Acetaminophen Diphenhydramine HCl

Strength
500 mg/1, 25 mg/1
Form
Tablet
Class
Histamine-1 Receptor Antagonist
OTC

Granules USA, Inc.

Not stocked by us — reference only

Acetaminophen PM

Acetaminophen, Diphenhydramine Hydrochloride

Strength
500 mg/1, 25 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist
OTC

Major Pharmaceuticals

Not stocked by us — reference only

ACETAMINOPHEN, DIPHENHYDRAMINE HCL

Strength
500 mg/1, 25 mg/1
Form
Tablet, Film Coated
Class
Histamine-1 Receptor Antagonist
OTC

CVS Pharmacy, Inc.

Not stocked by us — reference only

ADVIL PM

diphenhydramine HCl, ibuprofen

Strength
25 mg/1, 200 mg/1
Form
Capsule, Liquid Filled
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC

Haleon US Holdings LLC

Not stocked by us — reference only

ADVIL PM

diphenhydramine citrate and ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC

Haleon US Holdings LLC

Not stocked by us — reference only

ADVIL PM

diphenhydramine HCl, ibuprofen

Strength
25 mg/1, 200 mg/1
Form
Capsule, Liquid Filled
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC

Haleon US Holdings LLC

Not stocked by us — reference only

Advil PM

DIPHENHYDRAMINE CITRATE, IBUPROFEN

Strength
38 mg/1, 200 mg/1
Form
Tablet, Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC

Navajo Manufacturing Company Inc.

Not stocked by us — reference only

ADVIL PM

diphenhydramine citrate and ibuprofen

Strength
38 mg/1, 200 mg/1
Form
Tablet, Coated
Class
Histamine-1 Receptor Antagonist; Nonste…
OTC

Select Consumer Group

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.